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Oligonucleotide Sequence Confirmation for Quality Control by Micheal Ruhl from BioSpring

Mass spec is a reliable tool for oligonucleotide quality control. We show techniques on the BioAccord LC-MS System and Vion IMS QTof System to confirm the sequence of RNA and DNA oligo therapeutics covering adjuvant, siRNA, ASO, sgRNA and aptamers.

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