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Oligonucleotide Sequence Confirmation for Quality Control by Micheal Ruhl from BioSpring

Mass spec is a reliable tool for oligonucleotide quality control. We show techniques on the BioAccord LC-MS System and Vion IMS QTof System to confirm the sequence of RNA and DNA oligo therapeutics covering adjuvant, siRNA, ASO, sgRNA and aptamers.

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asms

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30:34
Guess How Many Samples - Breaking Boundaries in High-Throughput
Guess How Many Samples - Breaking Boundaries in High-Throughput
22:49
Metabolomics Profiling of Sebum and Serum to Monitor Progression Markers of Parkinson's Disease
Metabolomics Profiling of Sebum and Serum to Monitor Progression Markers of Parkinson's Disease
16:39
Bioanalytics of Oligonucleotides Using HRMS
Bioanalytics of Oligonucleotides Using HRMS
19:37
MAM Deployment for QC Analytical Testing and Substitution of Conventional Analytical Methods
MAM Deployment for QC Analytical Testing and Substitution of Conventional Analytical Methods
21:09
Oligonucleotide Sequence Confirmation for Quality Control by Micheal Ruhl from BioSpring
Oligonucleotide Sequence Confirmation for Quality Control by Micheal Ruhl from BioSpring
2:39
ASMS 2024 Recap Featuring the BioAccord LC-MS System for Accelerated Biopharmaceutical Analysis
ASMS 2024 Recap Featuring the BioAccord LC-MS System for Accelerated Biopharmaceutical Analysis
27:36
Hyphenation of non-denaturing chromatographic methods to native mass spectrometry and ion mobility for therapeutic protein characterization
Hyphenation of non-denaturing chromatographic methods to native mass spectrometry and ion mobility for therapeutic protein characterization
3:16
ASMS 2023 Teaser Dr.Maria Gomez
ASMS 2023 Teaser Dr.Maria Gomez
20:11
ASMS 2023 オンデマンド 代謝プロファイリング、質量分析および National Phenome Centre（ロンドン）
ASMS 2023 オンデマンド 代謝プロファイリング、質量分析および National Phenome Centre（ロンドン）
3:26
ASMS | Ruth Wamsley, Waters Corporation
ASMS | Ruth Wamsley, Waters Corporation
20:58
Meeting the Challenges of Implementing Accurate-Mass Mass Spectrometry for Biotherapeutic Development
Meeting the Challenges of Implementing Accurate-Mass Mass Spectrometry for Biotherapeutic Development
24:38
UNIFI Workgroup Computing - Promoting Collaboration in the Biologics Characterization MS Core Group
UNIFI Workgroup Computing - Promoting Collaboration in the Biologics Characterization MS Core Group
29:27
LC-MS Analysis of Plasma from Patients with Insulin Autoimmune Syndrome
LC-MS Analysis of Plasma from Patients with Insulin Autoimmune Syndrome
29:48
Using Low-Resolution MS for Protein Therapeutic Process Monitoring During Development After One-Time Characterization with High-Resolution MS
Using Low-Resolution MS for Protein Therapeutic Process Monitoring During Development After One-Time Characterization with High-Resolution MS
28:03
The Use of Progenesis QI to Efficiently Process Lipidomic Data: Application to Traumatic Brain Injury
The Use of Progenesis QI to Efficiently Process Lipidomic Data: Application to Traumatic Brain Injury

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