LC-MS for RNA Therapeutics to Ensure Product Quality and Process Consistency
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LC-MS for RNA Therapeutics to Ensure Product Quality and Process Consistency
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LC-MS for RNA Therapeutics to Ensure Product Quality and Process Consistency
Clone selection, early in the development lifecycle, has an outsize impact on the ability to match the quality target product profile (QTPP) for a given product.
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Watch this presentation to learn about the uses of the Xevo G3 QTof mass spectrometer in a case study of biosimilar mAb characterization at intact, subunit, and peptide level.
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Learn how Similis Bio implemented a streamlined mAb subunit LC-MS workflow for Multiple Attribute Monitoring of biosimilar mAb candidates during bioprocessing and development.
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Critical to the development of a biosimilar is understanding the originator and how its CQAs compare against the biosimilar. Learn about solutions that provide high quality peptide mapping, glycan and charge variant data.
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Released N-linked glycan analysis is the gold standard for N-glycan profiling of therapeutic monoclonal antibodies (mAbs) as they play an important role in safety and efficacy.
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Here we demonstrate how sample prep has been greatly simplified and automated to enable rapid LC-MS (intact and subunit) analysis at higher throughput, with less human intervention, all while providing high quality to support process development.
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